Latisse is an FDA-approved serum (bimatoprost ophthalmic solution, 0.03%) used to lengthen, thicken and darken eyelashes. It has the same main ingredient as a glaucoma drug called Lumigan.
Some people using Lumigan for glaucoma were surprised to find that they developed fuller, darker eyelashes. This desirable effect inspired the drug's use for cosmetic purposes.
Beauty aisles are filled with over-the-counter serums promising to mimic Latisse's effects. But there are important differences. Bimatoprost, the prostaglandin analog found in Latisse, is FDA approved. But isopropyl cloprostenate, the prostaglandin analog often found in over-the-counter products, is not. Because these over-the-counter serums have not been FDA tested, their safety and effects are not known. Lastisse is the only eyelash growth serum currently approved by the FDA.